PDRN vs Carboxy Therapy: Which Is Better for Your Skin?
Compare PDRN and Carboxy Therapy for skincare. Learn the differences in mechanism, results, and when to use each for optimal skin health.
Quick Comparison
| Mechanism | PDRN: DNA fragment signaling activates adenosine A2A receptors for cellular regeneration Carboxy Therapy: CO2 injection improves oxygenation and circulation |
|---|---|
| Primary Use | PDRN: Skin regeneration, wound healing, anti-aging Carboxy Therapy: Circulation, cellulite, dark circles |
| Molecular Weight | PDRN: 50-1500 kDa (optimized for skin penetration) Carboxy Therapy: N/A - gas |
| Penetration | PDRN: Injectable or enhanced topical delivery Carboxy Therapy: Subcutaneous |
| Irritation Potential | PDRN: Very Low Carboxy Therapy: Temporary discomfort |
How Does Carboxy Therapy Work?
Carboxy Therapy is a professional treatment that co2 injection improves oxygenation and circulation. It's primarily used for circulation, cellulite, dark circles.
With a molecular weight of N/A - gas, Carboxy Therapy has subcutaneous penetration capabilities. The irritation potential is temporary discomfort, making it best suited for those who can tolerate active ingredients.
How Does PDRN Compare?
PDRN (Polydeoxyribonucleotide) works through a fundamentally different mechanism. Derived from salmon DNA, PDRN provides nucleotide fragments that activate the adenosine A2A receptor pathway, triggering genuine cellular regeneration and tissue repair.
Improved tissue environment
Carboxy Therapy Best For
- Dark circles
- Circulation
- Cellulite
Carboxy Therapy Not Ideal For
- Respiratory issues
Can You Use PDRN and Carboxy Therapy Together?
Oxygenation + PDRN delivery
The Verdict
Circulation + repair combination
Frequently Asked Questions
What is the main difference between PDRN and Carboxy Therapy?
PDRN works through DNA fragment signaling to activate cellular repair and regeneration at a fundamental level. Carboxy Therapy co2 injection improves oxygenation and circulation. While both can benefit skin health, they work through completely different pathways.
Can I use PDRN and Carboxy Therapy in the same routine?
Oxygenation + PDRN delivery
Which is better for anti-aging: PDRN or Carboxy Therapy?
Improved tissue environment Circulation + repair combination
Is PDRN or Carboxy Therapy more irritating?
PDRN has very low irritation potential and is well-tolerated by most skin types. Carboxy Therapy has temporary discomfort irritation potential. Consider your skin sensitivity when choosing between them.