PDRN vs Myristoyl Pentapeptide-17: Which Is Better for Your Skin?
Compare PDRN and Myristoyl Pentapeptide-17 for skincare. Learn the differences in mechanism, results, and when to use each for optimal skin health.
Quick Comparison
| Mechanism | PDRN: DNA fragment signaling activates adenosine A2A receptors for cellular regeneration Myristoyl Pentapeptide-17: Stimulates keratin genes for lash and brow growth |
|---|---|
| Primary Use | PDRN: Skin regeneration, wound healing, anti-aging Myristoyl Pentapeptide-17: Lash growth, brow enhancement |
| Molecular Weight | PDRN: 50-1500 kDa (optimized for skin penetration) Myristoyl Pentapeptide-17: Variable |
| Penetration | PDRN: Injectable or enhanced topical delivery Myristoyl Pentapeptide-17: Targeted to follicles |
| Irritation Potential | PDRN: Very Low Myristoyl Pentapeptide-17: Very Low |
How Does Myristoyl Pentapeptide-17 Work?
Myristoyl Pentapeptide-17 is a hair growth peptide that stimulates keratin genes for lash and brow growth. It's primarily used for lash growth, brow enhancement.
With a molecular weight of Variable, Myristoyl Pentapeptide-17 has targeted to follicles penetration capabilities. The irritation potential is very low, making it suitable for most skin types.
How Does PDRN Compare?
PDRN (Polydeoxyribonucleotide) works through a fundamentally different mechanism. Derived from salmon DNA, PDRN provides nucleotide fragments that activate the adenosine A2A receptor pathway, triggering genuine cellular regeneration and tissue repair.
PDRN supports follicle health
Myristoyl Pentapeptide-17 Best For
- Sparse lashes
- Thin brows
Myristoyl Pentapeptide-17 Not Ideal For
- Eye sensitivity
Can You Use PDRN and Myristoyl Pentapeptide-17 Together?
Targeted hair growth application
The Verdict
Specialized peptide for lash/brow area
Frequently Asked Questions
What is the main difference between PDRN and Myristoyl Pentapeptide-17?
PDRN works through DNA fragment signaling to activate cellular repair and regeneration at a fundamental level. Myristoyl Pentapeptide-17 stimulates keratin genes for lash and brow growth. While both can benefit skin health, they work through completely different pathways.
Can I use PDRN and Myristoyl Pentapeptide-17 in the same routine?
Targeted hair growth application
Which is better for anti-aging: PDRN or Myristoyl Pentapeptide-17?
PDRN supports follicle health Specialized peptide for lash/brow area
Is PDRN or Myristoyl Pentapeptide-17 more irritating?
PDRN has very low irritation potential and is well-tolerated by most skin types. Myristoyl Pentapeptide-17 has very low irritation potential. Both are generally well-tolerated.